ABSTRACT
Introduction: The glucagon-like peptide-1 [GLP-1], is a neuropeptide and an incretin that helps regulate glucose and insulin concentrations. The effects of acute aerobic exercise however on the response of GLP-1 are unclear. The purpose of this study was to investigate the effect of acute aerobic exercise on glucagon -like peptide-1 [GLP-1] serum levels, glucose and insulin in women with type II diabetes mellitus
Materials and Methods: In this study, 20 patients with type II diabetes were enrolled in two groups [experimental and control]. The experimental group underwent aerobic training one times [running on treadmill] with moderate intensity 65-75% HR max to exhaustion. Blood samples before exercise, immediately after and 24 hours after exercise were collected for measuring GLP-1, glucose and Insulin
Results: Results showed that none of sampling time effects on GLP-1, glucose and insulin were significant [p>0.05]. also, Pearson correlation showed that was significant relationship between GLP-1 changes levels and glucose [p<0.05]
Conclusion: Results indicate that in women with type II diabetes, acute aerobic exercise, with moderate intensity to exhaustion immediately and 24 hours after exercise has no effect on serum levels of GLP-1, glucose and insulin
ABSTRACT
Introduction: the direct relationship between inflammation and resistance to insulin has been well codumented. It also has been demonstrated that the aim of this study was to evaluate the effect of eight weeks aerobic interval training on adiponectin serum levels, lipid profiles and HS-CRP in women with type II diabetes
Materials and Methods: in this study, 18 patients with type II diabetes were enrolled in two groups [experimental and control]. The experimental group underwent aerobic interval training and pedaling on the ergometer bicycle with 65 to 80 percent of their maximum leg power, three times a week for eight weeks. Blood samples were obtained in two pre-test and post-test steps to measure the adiponectin serum levels and HS-CRP by the ELISA method and lipid profiles using biochemical methods
Results: statistical analysis showed that after eight weeks of aerobic interval training, adiponectin serum levels, lipid profiles and HS-CRP of the experimental group showed no significant differences in comparison with the controls [p>0.05]
Conclusion: results indicate that in women with type II diabetes, aerobic interval training, three times a week, for eight weeks with 65 to 80 percent of maximum leg power, improves resistance to insulin but, has no effect on adiponectin serum levels, lipid profiles and HS-CRP